Chris,
This may sound shallow, but why not trying to match Zeggy's interface and then have people vote? I'm curious how much aesthetics sways things.
From a playability stand point, 2 things stood out to me.
1) This is a simple game. My expectations were not very high on optimization complexity. Thus, I actually preferred your original version to your second version.
2) Zeggy's interface is in many ways more friendly than yours. And as a player, I like friendly. And I'm not just talking looks or Ajax. Its much easier as a player to push a button to 'upgrade' an item (especially when there are only 4 choices)... but it is very difficult and scary to change the price of an item, choose and advertising technique, etc, when you're not familiar with the system. This makes your game difficult to get into. Also, with such a simple type game with no score board history, I found it difficult to convince myself to spend the time needed to learn your game. Yes, it is much more strategically centered, but the reward I experience from playing just isn't high enough to validate the bigger learning curve.